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Emerging applications for DNA writers and molecular recorders
Natural life is encoded by evolvable, DNA-based memory. Recent advances in dynamic genome-engineering technologies, which we collectively refer to as in vivo DNA writing, have opened new avenues for investigating and engineering biology. This Review surveys these technological advances, outlines their prospects and emerging applications, and discusses the features and current limitations of these technologies for building various genetic circuits for processing and recording information in living cells.
pmid: 30166483 Science 影响因子: 41.037 发表日期: 20180831 官网 免费下载
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