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Oncogene-induced senescence, e.g., in melanocytic nevi, terminates the expansion of pre-malignant...

期刊:Cancer Cell  影响因子:23.916  发表日期: 20180212  PMID: 29438700 


Angioimmunoblastic T?cell lymphoma (AITL) is an aggressive tumor derived from malignant transform...

期刊:Cancer Cell  影响因子:23.916  发表日期: 20180212  PMID: 29398449 


Aerobic glycolysis (the Warburg effect) facilitates tumor growth, and drugs targeting aerobic gly...

关键词: SIX1    Warburg effect    aerobic glycolysis    cancer    microRNA    transcription factor   
期刊:Cancer Cell  影响因子:23.916  发表日期: 20180208  PMID: 29455928 


The lysine-specific demethylase KDM1A is a key regulator of stem cell potential in acute myeloid ...

期刊:Cancer Cell  影响因子:23.916  发表日期: 20180223  PMID: 29502954 


Many cancer types are driven by oncogenic transcription factors that have been difficult to drug....

关键词: CDK12    DNA damage repair    EWS/FLI    Ewing sarcoma    PARP inhibitors    THZ1    THZ531    synthetic lethal   
期刊:Cancer Cell  影响因子:23.916  发表日期: 20180212  PMID: 29358035 


A quarter of all solid tumors harbor KRAS oncogenes. Yet, no selective drugs have been approved t...

期刊:Cancer Cell  影响因子:23.916  发表日期: 20180212  PMID: 29395869 


In this issue of Cancer Cell, Jeselsohn et?al. dissect the function of several of the most clinic...

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期刊:Cancer Cell  影响因子:23.916  发表日期: 20180212  PMID: 29438688 


The clinical efficacy of therapies targeting the PD-1/PD-L1 pathway is still limited. In this iss...

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期刊:Cancer Cell  影响因子:23.916  发表日期: 20180212  PMID: 29438689 


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