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Resistance to asparaginase, an antileukemic enzyme that depletes asparagine, is a common clinical...

期刊:Cancer Cell  影响因子:23.916  发表日期: 20190415  PMID: 30991026 


Using longitudinal molecular profiling, K?rber et?al. propose in this issue of Cancer Cell that I...

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期刊:Cancer Cell  影响因子:23.916  发表日期: 20190415  PMID: 30991024 


Long non-coding RNAs (lncRNAs) represent a huge reservoir of potential cancer targets. Such "onco...

关键词: CRISPR-Cas9    cancer    drug targets    genome editing    lncRNA    long non-coding RNA    screening   
期刊:Cancer Cell  影响因子:23.916  发表日期: 20190415  PMID: 30827888 


Tumor cells may adapt to metabolic challenges by alternating between glycolysis and oxidative pho...

关键词: GSK3?    MCL1    PP2A    caloric restriction    fasting    glucose    hypoglycemia    metabolic plasticity    metformin    tumor metabolism   
期刊:Cancer Cell  影响因子:23.916  发表日期: 20190410  PMID: 31031016 


The mitochondrial caseinolytic protease P (ClpP) plays a central role in mitochondrial protein qu...

期刊:Cancer Cell  影响因子:23.916  发表日期: 20190424  PMID: 31056398 


One of the key challenges in cancer research is how to effectively kill cancer cells while leavin...

关键词: GPX4    HMOX1    Iron    anti-cancer therapy    ferroptosis    lipid peroxidation    nanomedicine    p53   
期刊:Cancer Cell  影响因子:23.916  发表日期: 20190426  PMID: 31105042 


In this issue of Cancer Cell, Liao et?al. demonstrate that oncogenic KRAS drives an immune suppre...

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期刊:Cancer Cell  影响因子:23.916  发表日期: 20190415  PMID: 30991021 


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期刊:Cancer Cell  影响因子:23.916  发表日期: 20190415  PMID: 30991028 


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