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"Biased" G protein-coupled receptor (GPCR) agonists preferentially activate pathways mediated by ...



Covalent DNA-protein cross-links (DPCs) impede replication fork progression and threaten genome i...

期刊:Cell  影响因子:36.216  发表日期: 20190110  PMID: 30595447 


There are still gaps in our understanding of the complex processes by which p53 suppresses tumori...

关键词: ABCA1    SREBP-2    cancer metabolism    mevalonate pathway    p53    tumor suppression   
期刊:Cell  影响因子:36.216  发表日期: 20190124  PMID: 30580964 


Cannabis elicits its mood-enhancing and analgesic effects through the cannabinoid receptor 1 (CB1...

关键词: CB1    Fubinaca    G(i)    GPCR    cannabinoid receptor    cryo-EM    synthetic cannabinoid   
期刊:Cell  影响因子:36.216  发表日期: 20190124  PMID: 30639101 


Here, we present Perturb-ATAC, a method that combines multiplexed CRISPR interference or knockout...

期刊:Cell  影响因子:36.216  发表日期: 20190110  PMID: 30580963 


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期刊:Cell  影响因子:36.216  发表日期: 20190110  PMID: 30633908 


关键词:   
期刊:Cell  影响因子:36.216  发表日期: 20190110  PMID: 30633909 


Influenza viruses inhabit a wide range of host environments using a limited repertoire of protein...

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期刊:Cell  影响因子:36.216  发表日期: 20190110  PMID: 30503209 


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