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The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles ...

期刊:Genome Biol  影响因子:14.028  发表日期: 20190815  PMID: 31416467 


Cas9 nucleases can be programmed with single guide RNAs (sgRNAs) to mediate gene editing. High CR...

期刊:Cell Rep  影响因子:7.815  发表日期: 20190129  PMID: 30699341 


Xenopus tropicalis has been developed as a model organism for developmental biology, providing a ...



Pooled CRISPR screens allow researchers to interrogate genetic causes of complex phenotypes at th...

期刊:Genome Biol  影响因子:14.028  发表日期: 20181008  PMID: 30296940 


BACKGROUND: Genetic screens using CRISPR/Cas9 are a powerful method for the functional analysis o...

期刊:Genome Biol  影响因子:14.028  发表日期: 20160324  PMID: 27013184 


The CRISPR/Cas9 system and related RNA-guided endonucleases can introduce double-strand breaks (D...

期刊:Plant Biotechnol J  影响因子:6.84  发表日期: 20161201  PMID: 27614091 


Applying clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated pro...

期刊:Proc Natl Acad Sci USA  影响因子:9.58  发表日期: 20161101  PMID: 27729526 


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