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OBJECTIVE: To evaluate the tolerability for safflower peony ointment and determine its safe dosag...

目的:选择健康人为受试者,从安全的初始剂量开始,评估红花丹皮酚膏的耐受性以确定其安全剂量,为制定本品II期临床试验的给药方案提供依据。方法:共有46名健康受试者纳入耐受性研究,接受开放、随机、剂...

期刊:Zhongguo Zhong Yao Za Zhi  影响因子:0.0  发表日期: 20130101  PMID: 23596888 


BACKGROUND: Sampling the dermal interstitial fluid (ISF) allows the pharmacokinetics and pharmaco...

期刊:Skin Res Technol  影响因子:1.662  发表日期: 20131101  PMID: 23581539 


BACKGROUND: To review the available evidence from prospective studies on the safety and tolerabil...

期刊:World J Pediatr  影响因子:1.164  发表日期: 20171201  PMID: 28702868 


AIM: To assess the efficacy and tolerability of pericyazine in the treatment of patients with men...

期刊:Zh Nevrol Psikhiatr Im S S Korsakova  影响因子:0.0  发表日期: 20170101  PMID: 29171491 


Two randomized, double-blind, placebo-controlled studies are reported that had the objective to e...

关键词: ASP015K    peficitinib    pharmacodynamics    pharmacokinetics    safety    tolerability   
期刊:Clin Pharmacol Drug Dev  影响因子:0.0  发表日期: 20161101  PMID: 27162173 


BACKGROUND: The mammalian target of rapamycin (mTOR) inhibitor everolimus is approved (in combina...

期刊:Clin J Oncol Nurs  影响因子:0.627  发表日期: 20150801  PMID: 26207713 


Huperzine A is a potent, reversible, and blood-brain barrier permeable acetylcholinesterase inhib...

期刊:J Huazhong Univ Sci Technol Med Sci  影响因子:0.0  发表日期: 20171001  PMID: 29058298 


BACKGROUND: Regulations on medicinal products for paediatric use require that pharmacokinetics an...

期刊:Pediatr Allergy Immunol  影响因子:0.0  发表日期: 20160801  PMID: 26918853 


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